Postdoctoral Fellow - Dr. Dipa Pradhan-Sundd - Transfusion Medicine, Vascular Biology & Cell Therapy

Located in Milwaukee, Wisconsin, the Versiti Blood Research Institute (VBRI) is the largest blood-focused research institute in the United States. With over 30 basic, translational, and clinical researchers, the institute is dedicated to advancing scientific knowledge and developing innovative therapies related to blood and blood disorders. The institute's research interests encompass a wide range of topics, including transfusion medicine, cellular therapy, thrombosis/hemostasis, immunology, and hematologic malignancies. As a vital part of Versiti, a non-profit organization with a blood bank at its core, the VBRI strives to improve lives through innovative research and the development of novel diagnostics and treatments.

VBRI is part of the Milwaukee Regional Medical Campus, a rapidly growing clinical-translational research hub. VBRI's proximity to the Medical College of Wisconsin, Childrens' Hospital of Wisconsin, and Froedtert Hospital facilitates seamless interdisciplinary collaborations. A range of exemplary core facilities support highly competitive research. In the summer of 2024, construction of a new research building will start, doubling existing VBRI research space to enable the recruitment of 10-15 new faculty. With its renowned researchers, strategic expansion plans and location in a highly collaborative environment, the VBRI is poised to maintain and expand its position as one of the leading hematology institutes in the world.

A postdoctoral position is available at NIH-funded lab to study the role of HEMOLYSIS in promoting organ damage in SICKLE CELL DISEASE. The lab is interested in studying the role of hemolysis induced heme-iron -hemoglobin accumulation and associated liver-kidney and splenic injury in Sickle Cell Disease. Previous experience in mice surgery or intravital microscopy, microfluidic platforms, flow cytometry, western blot analysis and a strong background in hemoglobin-heme-iron clearance, liver biology, and sterile inflammation, receptor-ligand interaction and endocytosis is highly preferred.

Our labs are located in the Versiti Blood Research Institute (VBRI) of the Blood Center of Wisconsin in Milwaukee (https://versiti.org/versiti-blood-research-institute). VBRI is a leader in the field of thrombosis, hemostasis, benign/malignant hematology and genetic disorders like Sickle Cell Disease, VWF disease and hemophilia. VBRI's close association with the Versiti Medical Sciences Institute, the Versiti blood center of Wisconsin, the Medical College of Wisconsin and the Adult as well as Pediatric Sickle Cell Clinic at the Froedtert hospital and Children's Hospital of Wisconsin ensures strong translational training and accessibility to invaluable resources such as patient tissue/blood samples. VBRI has a strong commitment towards career development of young investigators in the field of basic and translational hematology. Postdoc candidates will also have the opportunity to learn basic and clinical hematology, innate immunity, thrombosis, platelet biology and pulmonary vascular biology. VBRI and the Milwaukee Regional Medical Center are located in Wauwatosa, which is a peaceful and beautiful suburb of Milwaukee, the second largest city in Mid-West US with affordable living cost. Milwaukee, situated on the shore of beautiful lake Michigan enjoys all four seasons and provides all the charms of a big city. In addition, the close proximity to Chicago city (70 miles) ensures accessibility to all the attractions in the city of Chicago. Travel to and from Milwaukee is convenient through either Milwaukee General Mitchell Airport or Ohare Chicago International Airport. Ohare Chicago is only 63 miles from Milwaukee and easily accessible via car, bus or train provides a convenient means of international air travel with direct flights to most destinations in the world.

Interested candidates are encouraged to send a brief cover letter, CV and the names and contact information of 3 references to: Dipa Pradhan-Sundd, PhD - tpradhan@versiti.org. Strong written and verbal skills in English are essential. PhDs from Cell Biology, Bioengineering, Biophysics, Biochemistry, Physiology, Immunology, pharmaceutical sciences, Pathology and Molecular Biology who aspire to establish themselves as independent investigators in pulmonary thrombosis are highly encouraged to apply. For more information about Dr. Pradhan-Sundd's lab, please review: https://versiti.org/our-experts/investigator/tirthadipa-pradhan-sundd

Benefits

Versiti provides a comprehensive benefits package based on your job classification. Full-time regular employes are eligible for Medical, Dental, and Vision Plans, Paid Time Off (PTO) and Holidays, Short- and Long-term disability, life insurance, 7% match dollar for dollar 401(k), voluntary programs, discount programs, others.

MAJOR RESPONSIBILITIES * Works with Principal Investigator to develop a research project. * Executes laboratory experiments specific to aims of research. * Troubleshoots assays and customizes experimental tools to answer research questions. * Coordinates external and internal resources necessary for completion of research plan. * Provides direction to Technologists and Trainees. * Generates clear and complete records of experimental work. * Communicates results of research at meetings. * Participates in publication and presentation of research.
• GENERAL DUTIES * Adheres to BCW, Bio-safety, NRC, OSHA procedures and regulations. * Attends required laboratory meetings. * Maintains currency with information relative to the field of research being performed. * Serves as a resource for techniques, information, instrumentation, interpretation of data, etc. for laboratory personnel * May be expected to help direct the work of Research Technologists. * Operates, calibrates and performs routine maintenance on specialized research equipment. * Prepares solutions, reagents, media or stains necessary for experimental procedures. * May maintain or oversee maintenance of inventory of laboratory supplies and equipment. * May prepare and/or authorize requisitions for ordering supplies and equipment. * Performs other laboratory duties as assigned.
• Performs other duties as assigned
• Complies with all policies and standards

Education

• PhD required
• equivalent degree required

Experience

• 0 - 6 years of postdoctoral training required

Knowledge, Skills and Abilities

• Demonstrated ability to independently apply understanding of scientific theory to the structure and execution of research experiments. required
• Demonstrated ability to interpret and explain the theoretical basis of the work performed. required
• Ability to perform research procedures independently. required
• Immediate proficiency in basic and sophisticated experimental tests and procedures. required
• Exceptional organizational skills. required
• Strong detail orientation and analytical ability. required
• Excellent problem solving skills. required
• Ability to prioritize and execute multiple tasks and meet deadlines. required
• Computer literate with an emphasis on graphics, graphing, data management, and statistical applications required

Tools and Technology

• Specialized research equipment required
• Personal computer required

#LI-EH1

#LI-Onsite

#VBRI