Director, Clinical Sciences and Trial Acceleration, Therapeutic Lead

Job Description Summary

Job Description

Key responsibilities

• Provide Clinical Science leadership for an assigned therapeutic area; partner with Medical Director/MST Lead to co-develop program strategy, evidence generation plans, and study concepts aligned to portfolio priorities.

• Serve as Clinical Science lead on the MST and represent US Medical Affairs in key cross-functional forums and workstreams.

• Lead scientific review, prioritization, and oversight of Investigator Initiated Trials (IITs) in partnership with Medical Affairs and governance stakeholders.

• Lead and support external research collaborations (e.g., academic partnerships, consortium-based studies) from concept through execution, ensuring scientific quality and operational rigor.

• Ensure consistent clinical science standards, governance, and best practices across IITs and external collaborations.

• Drive Medical Office clinical trial acceleration across USMA to reduce cycle times and improve study start-up and execution.

• Coordinate trial acceleration activities across Clinical Sciences, Medical Affairs, and cross-functional partners; establish clear milestones, owners, and accountability.

• Identify, prioritize, and execute acceleration initiatives; translate strategic objectives into measurable operational impact (timelines, throughput, quality).

• Act as an integrator across enabling functions (e.g., medical leadership, field medical, governance, contracts) to implement scalable acceleration ways of working.

• Lead evidence generation acceleration initiatives (e.g., portfolio control tower approach, acceleration playbooks, external collaboration strategy).

• Track, communicate, and continuously improve outcomes using data-driven insights, dashboards, and performance metrics.

• Provide scientific and operational oversight for assigned studies/programs, including feasibility input and contributions to protocols and key study documents.

• Oversee vendor, budget, and resource planning as applicable; ensure accurate forecasting and delivery against commitments.

• Lead, coach, and develop a team of trial leads and/or matrixed resources; support hiring, retention, and capability building.

• Ensure compliance with SOPs, GCP, and ethical requirements; contribute to continuous improvement of processes and working practices.

Essential requirements

• Bachelor's degree in a science-related field required; advanced degree (Master's/PhD) preferred or equivalent certification/licensure.

• Minimum 8 years of relevant clinical research/clinical science experience, including mentoring/training others and leading complex cross-functional initiatives.

• Demonstrated experience leading high-priority process improvement/transformation initiatives, ideally focused on cycle-time reduction and operational execution.

• Strong working knowledge of FDA guidelines, GCP, and applicable SOPs; ability to evaluate medical research data and apply medical/scientific terminology.

• Strong written, oral, and presentation skills; ability to communicate strategy, develop/review protocols, assess feasibility, and present to senior leaders.

• Proven ability to work independently with minimal oversight, drive accountability in matrix environments, and deliver measurable outcomes through influence.

• Proficiency with Microsoft Office (especially PowerPoint); ability to learn proprietary systems and leverage metrics for performance management.

• Prior experience leading clinical trial acceleration

Novartis Compensation Summary:

The salary for this position is expected to range between $204,400 and $379,600 per year.

The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.

Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.

US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.

To learn more about the culture, rewards and benefits we offer our people click here.

EEO Statement:

The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.

Accessibility and reasonable accommodations

The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to us.reasonableaccommodations@novartis.com or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Salary Range

Skills Desired