Scientist

Job Title: Scientist

Duration: 12 months (potential extension based on performance and business needs)

Location/Site: North Chicago, IL, 60064 - 100% onsite

Location: LC - Abbott Park - 100% Onsite

Purpose:

The primary functions of this position are conducting laboratory experiments and analysis in support of molecular toxicology studies.

Key responsibilities:

* The candidate must be able to multi-task and collaborate successfully across other groups within R&D to identify optimal screening assays for early detection of toxicity liabilities

* Support Preclinical Safety Toxicologists and Pathologists with key in vitro platforms for investigating molecular mechanisms of toxicity and enabling optimal selection of drug candidates.

* Develop/characterize 2D/3D in vitro platforms, focused on toxicology.

* Conduct routine in vitro screening assays for early drug candidates.

* Produce/coordinate/present key data as needed.

* Analyze and interpret relevant molecular toxicology data in a timely manner and communicate data and interpretation to project stakeholders

Qualifications:

* BS or MS in cell/molecular biology, Molecular toxicology/Pharmacology, biochemistry, or a related field with 1-5+ yrs experience

* Experience in basic cell culture and cell biology endpoints. Knowledge of spheroid/organoid culture is a plus.

* Functional understanding of fluorescence and luminescence assays and related plate readers

* Practical knowledge of in vitro assay development and troubleshooting, ability to work in a rapid pace environment

* Good analytical skills and knowledge in data analysis, interpretation, report writing, and communication (both written and oral)

* Knowledge of traditional scientific, statistical, and graphing software

What are the top 3-5 skills, experience or education required for this position:

1. cell culture 2D a must, 3D would be a plus

2. in vitro assay experience

3. familiarity with luminescence/fluorescence/UV-Vis assay readout

4. familiarity with spheroids/organoids