Information Sciences Program Manager

Job Summary:

This position is for a Program Manager in the Stranger Lab in the Department of Biomedical Informatics. The overall goal of the research group is to discover new insights into genome function and the genetic basis of complex human phenotypes through analysis of diverse genetics, genomics, and clinical data. The Stranger Lab is at the forefront of groundbreaking research, merging human genetics, bioinformatics, statistical analysis of multidimensional data, and cutting-edge computer science to unravel the complexities of health and disease. By innovating methods to identify and interpret context-specific genetic effects, the lab is advancing discoveries on the impact of sex and gender on the genetics of complex traits. Our current research spans critical areas including cancer, neuropsychiatric and cardiac traits, immune-mediated traits, clinical laboratory tests, and women's health. We are seeking a passionate individual who is driven to significantly impact the field through groundbreaking research and inventive solutions.

The Program Manager will be expected to work independently and in collaboration with other members of the research group and other teams on campus and nationally and internationally. They will provide professional and scientifically rigorous statistical genetics and informatics expertise. This may include workflow and tool development, development and testing of computational and analytic solutions, study design and analytic consultation, biostatistics expertise, data visualization techniques, support and mentorship of junior lab members, grant writing, and dissemination of results to a variety of audiences with varying levels of computational and statistical expertise. Primary authorship and co-authorship on abstracts, oral and poster presentations, and scientific manuscripts will be involved. Preference will be given to those with a strong background in human statistical genetics and genomics, broad computational skills, and experience with complex data structures, distributed analytic tools, techniques for reproducibility, and open-source solutions.

The Program Manager will join a highly interactive, supportive, and interdisciplinary group of faculty, staff scientists, postdoctoral fellows, engineers, and students in the Department for Biomedical Informatics who are inventing and deploying advanced analytics and knowledge integration approaches. They will also join the thriving community of the Ludeman Family Center for Women's Health Research that supports women's health research and the researchers leading discoveries in sex and gender medicine and women's health. The goal of building this community is to make the Anschutz Medical Campus a leader in translating data into advances in research discoveries, health care delivery, and population health and in scaling these to provide nationwide benefit through innovative technologies.

Key Responsibilities:

• Design and lead data management, processing, and analysis using a variety of methods, approaches, and visualizations, including development of new computational solutions.
• Develop and implement complex analyses pipelines, programming, and data visualization techniques for multi-layered genetic, clinical, and -omics datasets (transcriptome, epigenome, proteome, microbiome, etc.).
• Write and submit grant proposals to secure funding for research projects.
• Oversee and provide informal leadership to the team members, including managing day-to-day priorities, evaluating and redistributing workloads on a temporary basis, and mentoring staff.
• Disseminate research findings by writing and publishing in peer-reviewed journals and presenting at national and international conferences.
• Develop and disseminate a variety of tools designed to access relevant clinical and sample data.
• Manage laboratory resources, maintain website, and ensure compliance with institutional and federal regulations.

Work Location:

Hybrid - this role is eligible for a hybrid schedule of 3 days per week on campus and as needed for in-person meetings.

Why Join Us:

The Department of Biomedical Informatics (DBMI), located in the magnificent new Health Science building with a fabulous view of the Rocky Mountains, provides a fantastic environment for faculty to thrive and pursue their career goals. DBMI has a dedicated team for Grants Development and Scientific Writing, and a Software Engineering Team that can provide invaluable feedback to improve the quality of your code and your programming skills. Furthermore, we have access to the biobank of the Colorado Center for Personalized Medicine, a large biorepository of genetic and clinical data that serves as a critical resource for genetic research.

The Stranger Lab at DBMI provides a dynamic and innovative environment where cutting-edge genetics research integrates with sex differences and women's health. Collaborate daily with statistical geneticists, bioinformaticians, computer scientists, and medical doctors to make biomedical discoveries to improve health for all. As the largest academic health sciences campus in the Rocky Mountain region, CU Anschutz encompasses six health professional schools, over 60 centers and institutes, and two nationally ranked partner hospitals. This vibrant department offers unique opportunities for growth, collaboration, and impact. Our location not only provides unprecedented access to urban amenities and cultural experiences in Denver but also places you minutes away from some of the nation's best outdoor activities, including hiking in the Rocky Mountains and skiing in Vail and Aspen.

The University of Colorado Denver | Anschutz Medical Campus is a public research university serving more than 18,000 students. We award nearly 4,000 degrees each year, including more graduate and professional degrees than any other Colorado institution. With our solid academic reputation, award-winning faculty and renowned researchers, we offer more than 140 highly rated degree programs through 13 schools and colleges. The university receives over $400 million in research awards each year. In addition to the wide array of health-related programs and facilities offered at CU Anschutz in Aurora, Colo. a significant number of undergraduate and graduate degree programs are taught at CU Denver, our comprehensive campus in the heart of downtown Denver-one of America's most vibrant urban centers. CU Denver is located steps from the Denver Center for Performing Arts and the LoDo District affording our students, faculty, and staff access to a broad array of academic, professional, community, recreational and cultural outlets.

Why work for the University?

We have AMAZING benefits and offer exceptional amounts of holiday, vacation and sick leave! The University of Colorado offers an excellent benefits package including:

• Medical: Multiple plan options
• Dental: Multiple plan options
• Additional Insurance: Disability, Life, Vision
• Retirement 401(a) Plan: Employer contributes 10% of your gross pay
• Paid Time Off: Accruals over the year
• Vacation Days: 22/year (maximum accrual 352 hours)
• Sick Days: 15/year (unlimited maximum accrual)
• Holiday Days: 10/year
• Tuition Benefit: Employees have access to this benefit on all CU campuses
• ECO Pass: Reduced rate RTD Bus and light rail service

There are many additional perks & programs with the CU Advantage.

Diversity and Equity:

The University of Colorado Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. We encourage applications from women, ethnically minoritized individuals, persons with disabilities, persons within the LGBTQ+ community and all veterans. In addition, the Anschutz Campus has also been recognized as an Age-Friendly University. The University of Colorado is committed to diversity and equality in education and employment.

Qualifications:

Minimum Qualifications:

• Bachelor's degree in Bioinformatics, Biostatistics, Computational Biology, Data Science, Computer Science or related field.
• Four (4) years of experience analyzing human genetics and genomics data using high-performance computing.

A combination of education and related technical/paraprofessional experience may be substituted for the bachelor's degree on a year for year basis.

Applicants must meet minimum qualifications at the time of hire.

Preferred Qualifications:

• Master's degree of higher in Statistical Genetics, Human Genetics, Computational Biology, Computer Science, Biostatistics, or related field.
• Five (5) or more years professional experience analyzing human genetics and genomics data.
• Five (5) or more years professional experience with distributed and cloud computing, version control, and techniques for reproducibility.
• Experience working with human sex chromosome genetics and genomics data.

Knowledge, Skills and Abilities:

• Ability to communicate effectively, both in writing and orally and the ability to disseminate results to a wide variety of audiences.
• Ability to establish and maintain effective working relationships with employees at all levels throughout the institution and the ability to work with a variety of investigators and colleagues.
• Demonstrated commitment and leadership ability to advance diversity and inclusion.
• Expert knowledge of basic statistical principles relevant in medical research.
• Expert ability to analyze and solve complex problems and apply quantitative analytical approaches.
• Demonstrated fluency in one or more programming languages (e.g., R, Python, Perl, Java, C++) and willingness to learn new programming languages as necessary.
• Familiarity with statistical analytical concepts and methods.
• Ability to interpret and master complex research protocol information.
• Expert level knowledge of statistical genetics, computational biology, and biostatistics
• Expert knowledge of statistical principles relevant in human population genetics, statistical genetics, and genomics research.
• Expert knowledge of standard genetics research resources, e.g. biobanks, Consortia, and standard computational tools and approaches.
• Strong skills in data visualization.
• Possess intellectual curiosity and a commitment to health equity, as well as interest in women's health and sex differences.
• Good organizational skills across multiple projects and the ability to manage one's own work load; self-directed.

How to Apply:

For full consideration, please submit the following document(s):

1. A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position

2. Curriculum vitae / Resume

3. Three to five professional references, including name, address, phone number (mobile number if appropriate), and email address

Questions should be directed to: DBMI HR, dbmi.hr@cuanschutz.edu

Screening of Applications Begins:

Applications will be accepted until finalists are identified, but preference will be given to complete applications received by December 1st, 2024. Those who do not apply by this date may or may not be considered.

Anticipated Pay Range:

The starting salary range (or hiring range) for this position has been established as $71,807 - $84,000.

The above salary range (or hiring range) represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting. This position may be eligible for overtime compensation, depending on the level.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.

Total Compensation Calculator: http://www.cu.edu/node/153125

ADA Statement:

The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at hr.adacoordinator@cuanschutz.edu.

Background Check Statement:

The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.

Vaccination Statement:

CU Anschutz strongly encourages vaccination against the COVID-19 virus and other vaccine preventable diseases. If you work, visit, or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz, you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work, visit, or volunteer, respectively. In addition, if you work in certain research areas or perform certain safety sensitive job duties, you must enroll in the occupational health medical surveillance program.