Staff Research Associate II

CoLabs Admin

Full Time

81373BR

Job Summary

The Staff Research Associate 2 (SRA 2) will perform, under supervision, state of the art molecular genetic approaches, including spatial transcriptomics, single cell transcriptomics and epigenomics methods. The successful candidate will join both the Genomics and D2B CoLab teams, where they will be responsible for the meticulous handling and processing of research and clinical samples The individual will work under general supervision and utilize problem solving skills to execute experimental methods. The SRA 2 use various protocols to generate next generation sequencing (NGS) libraries from DNA and RNA. They will closely interact with other laboratory members in the Genomics CoLab and collaborate extensively with Dr. Combes' group in the Disease to Biology (D2B) CoLab. The D2B CoLab is a collaborative research lab focusses on using single cell technologies to study immune cell networks. In the D2B CoLab a typical workflow involves processing tissue samples by digesting them into single cells, staining them for flow cytometry, and sorting them to generate cutting-edge single-cell multi-omics data. This approach enables precise dissection of the cellular composition and the transcriptomic and genomic signatures of the obtained tissue. Their duties will include both manual and automated preparation of cell digestion, flow cytometry analysis, RNA/DNA isolation, and the creation of sequencing libraries from model organisms and clinical samples. Additionally, they will be responsible for pre-processing and conducting basic analysis of sample preparation quality control results and next-generation sequencing data. The research associate will also aid in new and ongoing research projects involving other sample types and will perform other duties as assigned. Strong organization skills are required. The ideal candidate will have a familiarity with NGS technology and molecular genetics principles. The candidate will work under supervision on multiple projects utilizing project management skills to achieve expected results in specific timelines. This position represents an excellent opportunity to further basic laboratory and high-throughput molecular biology skills in a dynamic, well-established functional genomics research environment.

The final salary and offer components are subject to additional approvals based on UC policy.

Your placement within the salary range is dependent on a number of factors including your work experience and internal equity within this position classification at UCSF. For positions that are represented by a labor union, placement within the salary range will be guided by the rules in the collective bargaining agreement.

The salary range for this position is $28.04 - $45.09 (Hourly Rate).

To learn more about the benefits of working at UCSF, including total compensation, please visit: https://ucnet.universityofcalifornia.edu/compensation-and-benefits/index.html

Department Description

The CoLabs are a collection of integrated laboratories specializing in infrastructure or technologies. It seeks to revitalize the model for core resources by capitalizing on critical personnel and cutting-edge technologies and driving collaboration across disciplines. The model will house all CoLabs teams in a contiguous space and create a set of common pipelines and workflows in one centralized locale. It will recruit and retain world-class staff through project engagement, backstopped "tenure," and annual operational funds. It will develop and invest in transformative methods and technologies.

In its current form, the CoLabs consolidate three existing groups, Genomics, Flow Cytometry, and Biological Imaging Development (BIDC), and establish two new ones, Disease to Biology (D2B) and Data Science (DS), placing them all under one roof. The CoLabs will help organize and integrate the UCSF community through common pipelines and data curation around a set of collaborative "CoProjects" that will tackle fundamental questions in the field. While CoProjects are investigator-driven, the day-to-day operations must be managed and run through the cutting-edge CoLabs, which house world-class staff and technologies.

Genomics CoLab
The Genomics CoLab serves as an innovative hub of molecular biologists, genomicists and bioinformaticians engaging in collaborative research across UCSF campuses. At the Genomics CoLab, we emphasize in the development of novel genomic approaches and providing advanced genomic and bioinformatic resources for investigators who wish to integrate modern genomic approaches into biological research. These approaches include bulk- and single-cell RNA-seq, small RNA-Seq, ChIP-Seq, ATAC-seq and whole exome/genome sequencing. We are also actively working on integrating novel genomic methods such as combinatorial genomic methods, special transcriptomics, and new epigenomic approaches such as CUT&TAG.

Required Qualifications

• BA/BS in Biology, Molecular Biology or a related scientific field or equivalent combination of education and experience, plus 1 year of relevant experience and/or equivalent combination of education and experience.
• Experience with general molecular biology techniques.
• Excellent organization skills
• Willingness and ability to learn new methods and skills for changing research projects.
• Ability to work as a member of a research team.
• Strong interpersonal communication skills (verbal and written)
• Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines.

Preferred Qualifications

• Prior experience with molecular biology techniques, especially RNA assays
• Familiarity with MS Excel
• Familiarity with next generation sequencing methods

About UCSF

The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world's leading experts in nearly every area of health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells.

Pride Values

UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence - also known as our PRIDE values.

In addition to our PRIDE values, UCSF is committed to equity - both in how we deliver care as well as our workforce. We are committed to building a broadly diverse community, nurturing a culture that is welcoming and supportive, and engaging diverse ideas for the provision of culturally competent education, discovery, and patient care. Additional information about UCSF is available at diversity.ucsf.edu

Join us to find a rewarding career contributing to improving healthcare worldwide.

Equal Employment Opportunity

The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information.

Organization

Campus

Job Code and Payroll Title

009617 SRA 2 NEX

Job Category

Research and Scientific

Bargaining Unit

University Professional Technical Employees - Research Support Professionals Unit (UPTE-RX)

Employee Class

Career

Percentage

100%

Location

San Francisco, CA

Campus

Mission Bay (SF), Parnassus Heights (SF)

Work Style

Fully On-Site

Shift

Days

Shift Length

8 Hours

Additional Shift Details

Monday to Friday; 9am to 5:30pm